Computational Model Library

A minimal genetic algorithm was preliminarily developed to search for the solution of an elementary arithmetic problem. It has been modified to explore the effect of a mutator gene and the consequent entrance into a hypermutation state. The phenomenon is particularly important in some types of tumorigenesis and in a more general way, in cells and tissues submitted to chronic sublethal environmental or genomic stress.
Since a long time, some scholars suppose that organisms speed up their own evolution by varying mutation rate, but evolutionary biologists are not convinced that evolution can select a mechanism promoting more (often harmful) mutations looking forward an environmental challenge. The aim of the model is to shed light on these controversial points of views.

This model was developed to test the usability of evolutionary computing and reinforcement learning by extending a well known agent-based model. Sugarscape (Epstein & Axtell, 1996) has been used to demonstrate migration, trade, wealth inequality, disease processes, sex, culture, and conflict. It is on conflict that this model is focused to demonstrate how machine learning methodologies could be applied.

The code is based on the Sugarscape 2 Constant Growback model, availble in the NetLogo models library. New code was added into the existing model while removing code that was not needed and modifying existing code to support the changes. Support for the original movement rule was retained while evolutionary computing, Q-Learning, and SARSA Learning were added.

Peer reviewed MOOvPOPsurveillance

Aniruddha Belsare Matthew Gompper Joshua J Millspaugh | Published Tue Apr 4 17:03:40 2017 | Last modified Tue May 12 16:37:24 2020

MOOvPOPsurveillance was developed as a tool for wildlife agencies to guide collection and analysis of disease surveillance data that relies on non-probabilistic methods like harvest-based sampling.

Peer reviewed MOOvPOP

Aniruddha Belsare Matthew Gompper Joshua J Millspaugh | Published Mon Apr 10 20:03:42 2017 | Last modified Tue May 12 06:14:14 2020

MOOvPOP is designed to simulate population dynamics (abundance, sex-age composition and distribution in the landscape) of white-tailed deer (Odocoileus virginianus) for a selected sampling region.

This agent-based model was built as part of a replication effort of Jeness et al.’s work (linked below). The model simulates an MSM sexual activity network for the purpose of modeling the effects of respectively PrEP and ART on HIV prevention. The purpose of the model is to explore the differences between differerent interpretations of the NIH Indication Guidelines for PrEP.

This model extends the original Artifical Anasazi (AA) model to include individual agents, who vary in age and sex, and are aggregated into households. This allows more realistic simulations of population dynamics within the Long House Valley of Arizona from AD 800 to 1350 than are possible in the original model. The parts of this model that are directly derived from the AA model are based on Janssen’s 1999 Netlogo implementation of the model; the code for all extensions and adaptations in the model described here (the Artificial Long House Valley (ALHV) model) have been written by the authors. The AA model included only ideal and homogeneous “individuals” who do not participate in the population processes (e.g., birth and death)–these processes were assumed to act on entire households only. The ALHV model incorporates actual individual agents and all demographic processes affect these individuals. Individuals are aggregated into households that participate in annual agricultural and demographic cycles. Thus, the ALHV model is a combination of individual processes (birth and death) and household-level processes (e.g., finding suitable agriculture plots).

As is the case for the AA model, the ALHV model makes use of detailed archaeological and paleoenvironmental data from the Long House Valley and the adjacent areas in Arizona. It also uses the same methods as the original model (from Janssen’s Netlogo implementation) to estimate annual maize productivity of various agricultural zones within the valley. These estimates are used to determine suitable locations for households and farms during each year of the simulation.

Peer reviewed Evolution of Sex

Kristin Crouse | Published Sun Jun 5 08:24:01 2016 | Last modified Thu Feb 20 22:54:34 2020

Evolution of Sex is a NetLogo model that illustrates the advantages and disadvantages of sexual and asexual reproductive strategies. It seeks to demonstrate the answer to the question “Why do we have sex?”

NetLogo HIV spread model

Wouter Vermeer | Published Fri Oct 25 16:51:17 2019

This model describes the tranmission of HIV by means of unprotected anal intercourse in a population of men-who-have-sex-with-men.
The model is parameterized based on field data from a cohort study conducted in Atlanta Georgia.

The current rate of production and consumption of meat poses a problem both to peoples’ health and to the environment. This work aims to develop a simulation of peoples’ meat consumption behaviour in Britain using agent-based modelling. The agents represent individual consumers. The key variables that characterise agents include sex, age, monthly income, perception of the living cost, and concerns about the impact of meat on the environment, health, and animal welfare. A process of peer influence is modelled with respect to the agents’ concerns. Influence spreads across two eating networks (i.e. co-workers and household members) depending on the time of day, day of the week, and agents’ employment status. Data from a representative sample of British consumers is used to empirically ground the model. Different experiments are run simulating interventions of application of social marketing campaigns and a rise in price of meat. The main outcome is the average weekly consumption of meat per consumer. A secondary outcome is the likelihood of eating meat.

We compare three model estimates for the time and treatment requirements to eliminate HCV among HIV-positive MSM in Victoria, Australia: a compartmental model; an ABM parametrized by surveillance data; and an ABM with a more heterogeneous population.

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