Computational Model Library

Peer reviewed HyperMu’NmGA - Effect of Hypermutation Cycles in a NetLogo Minimal Genetic Algorithm

Cosimo Leuci | Published Tue Oct 27 21:15:40 2020 | Last modified Sun Jul 31 09:08:14 2022

A minimal genetic algorithm was preliminarily developed to search for the solution of an elementary arithmetic problem. It has been modified to explore the effect of a mutator gene and the consequent entrance into a hypermutation state. The phenomenon is particularly important in some types of tumorigenesis and in a more general way, in cells and tissues submitted to chronic sublethal environmental or genomic stress.
Since a long time, some scholars suppose that organisms speed up their own evolution by varying mutation rate, but evolutionary biologists are not convinced that evolution can select a mechanism promoting more (often harmful) mutations looking forward an environmental challenge.
The model aims to shed light on these controversial points of view and it provides also the features required to check the role of sex and genetic recombination in the mutator genes diffusion.

Peer reviewed Evolution of Sex

Kristin Crouse | Published Sun Jun 5 08:24:01 2016 | Last modified Mon Feb 15 15:40:39 2021

Evolution of Sex is a NetLogo model that illustrates the advantages and disadvantages of sexual and asexual reproductive strategies. It seeks to demonstrate the answer to the question “Why do we have sex?”

00 PSoup V1.22 – Primordial Soup

Garvin Boyle | Published Thu Apr 13 21:03:10 2017

PSoup is an educational program in which evolution is demonstrated, on the desk-top, as you watch. Blind bugs evolve sophisticated heuristic search algorithms to be the best at finding food fast.

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