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A minimal genetic algorithm was preliminarily developed to search for the solution of an elementary arithmetic problem. It has been modified to explore the effect of a mutator gene and the consequent entrance into a hypermutation state. The phenomenon is particularly important in some types of tumorigenesis and in a more general way, in cells and tissues submitted to chronic sublethal environmental or genomic stress.
Since a long time, some scholars suppose that organisms speed up their own evolution by varying mutation rate, but evolutionary biologists are not convinced that evolution can select a mechanism promoting more (often harmful) mutations looking forward an environmental challenge.
The model aims to shed light on these controversial points of view and it provides also the features required to check the role of sex and genetic recombination in the mutator genes diffusion.
This model is an extension of the Artificial Long House Valley (ALHV) model developed by the authors (Swedlund et al. 2016; Warren and Sattenspiel 2020). The ALHV model simulates the population dynamics of individuals within the Long House Valley of Arizona from AD 800 to 1350. Individuals are aggregated into households that participate in annual agricultural and demographic cycles. The present version of the model incorporates features of the ALHV model including realistic age-specific fertility and mortality and, in addition, it adds the Black Mesa environment and population, as well as additional methods to allow migration between the two regions.
As is the case for previous versions of the ALHV model as well as the Artificial Anasazi (AA) model from which the ALHV model was derived (Axtell et al. 2002; Janssen 2009), this version makes use of detailed archaeological and paleoenvironmental data from the Long House Valley and the adjacent areas in Arizona. It also uses the same methods as the original AA model to estimate annual maize productivity of various agricultural zones within the Long House Valley. A new environment and associated methods have been developed for Black Mesa. Productivity estimates from both regions are used to determine suitable locations for households and farms during each year of the simulation.
This model extends the original Artifical Anasazi (AA) model to include individual agents, who vary in age and sex, and are aggregated into households. This allows more realistic simulations of population dynamics within the Long House Valley of Arizona from AD 800 to 1350 than are possible in the original model. The parts of this model that are directly derived from the AA model are based on Janssen’s 1999 Netlogo implementation of the model; the code for all extensions and adaptations in the model described here (the Artificial Long House Valley (ALHV) model) have been written by the authors. The AA model included only ideal and homogeneous “individuals” who do not participate in the population processes (e.g., birth and death)–these processes were assumed to act on entire households only. The ALHV model incorporates actual individual agents and all demographic processes affect these individuals. Individuals are aggregated into households that participate in annual agricultural and demographic cycles. Thus, the ALHV model is a combination of individual processes (birth and death) and household-level processes (e.g., finding suitable agriculture plots).
As is the case for the AA model, the ALHV model makes use of detailed archaeological and paleoenvironmental data from the Long House Valley and the adjacent areas in Arizona. It also uses the same methods as the original model (from Janssen’s Netlogo implementation) to estimate annual maize productivity of various agricultural zones within the valley. These estimates are used to determine suitable locations for households and farms during each year of the simulation.