Model of the Corona pandemic outbreak

The COVID-19 ABM aims to predict the qualitative behaviour of the CoViD-19 epidemic dynamics for the greater region of Salzburg City. Specifically, by means of scenario testing, it aims to help assessing how containment interventions can allow a stepwise relaxation of the lockdown without risking a new outbreak.

This is an extension of the basic Suceptible, Infected, Recovered (SIR) model. This model explores the spread of disease in two spaces, one a treatment, and one a control. Through the modeling options, one can explore how changing assumptions about the number of susceptible people, starting number of infected people, the disease’s infection probability, and average duration impacts the outcome. In addition, this version allows users to explore how public health interventions like social distancing, masking, and isolation can affect the number of people infected. The model shows that the interactions of agents, and the interventions can drastically affect the results of the model.

We used the model in our course about COVID-19: https://www.csats.psu.edu/science-of-covid19

This model is intended to explore the effectiveness of different courses of interventions on an abstract population of infections. Illustrative findings highlight the importance of the mechanisms for variability and mutation on the effectiveness of different interventions.

The purpose of this curricular model is to teach students the basics of modeling complex systems using agent-based modeling. It is a simple SIR model that simulates how a disease spreads through a population as its members change from susceptible to infected to recovered and then back to susceptible. The dynamics of the model are such that there are multiple emergent outcomes depending on the parameter settings, initial conditions, and chance.

The curricular model can be used with the chapter Agent-Based Modeling in Mixed Methods Research (Moritz et al. 2022) in the Handbook of Teaching Qualitative & Mixed Methods (Ruth et al. 2022).

The instructional videos can be accessed on YouTube: Video 1 (https://youtu.be/32_JIfBodWs); Video 2 (https://youtu.be/0PK_zVKNcp8); and Video 3 (https://youtu.be/0bT0_mYSAJ8).

The purpose of this model is to better understand the dynamics of a multihost pathogen in two host system comprising of high densities of domestic hosts and sympatric wildlife hosts susceptible to the pathogen.

The model is a combination of a spatially explicit, stochastic, agent-based model for wild boars (Sus scrofa L.) and an epidemiological model for the Classical Swine Fever (CSF) virus infecting the wild boars.

The original model (Kramer-Schadt et al. 2009) was used to assess intrinsic (system immanent host-pathogen interaction and host life-history) and extrinsic (spatial extent and density) factors contributing to the long-term persistence of the disease and has further been used to assess the effects of intrinsic dynamics (Lange et al. 2012a) and indirect transmission (Lange et al. 2016) on the disease course. In an applied context, the model was used to test the efficiency of spatiotemporal vaccination regimes (Lange et al. 2012b) as well as the risk of disease spread in the country of Denmark (Alban et al. 2005).

References: See ODD model description.

In this model, the spread of a virus disease in a network consisting of school pupils, employed, and umemployed people is simulated. The special feature in this model is the distinction between different types of links: family-, friends-, school-, or work-links. In this way, different governmental measures can be implemented in order to decelerate or stop the transmission.

Leptospirosis is a neglected, bacterial zoonosis with worldwide distribution, primarily a disease of poverty. More than 200 pathogenic serovars of Leptospira bacteria exist, and a variety of species may act as reservoirs for these serovars. Human infection is the result of direct or indirect contact with Leptospira bacteria in the urine of infected animal hosts, primarily livestock, dogs, and rodents. There is increasing evidence that dogs and dog-adapted serovar Canicola play an important role in the burden of leptospirosis in humans in marginalized urban communities. What is needed is a more thorough understanding of the transmission dynamics of Leptospira in these marginalized urban communities, specifically the relative importance of dogs and rodents in the transmission of Leptospira to humans. This understanding will be vital for identifying meaningful intervention strategies.
One of the main objectives of MHMSLeptoDy is to elucidate transmission dynamics of host-adapted Leptospira strains in multi-host system. The model can also be used to evaluate alternate interventions aimed at reducing human infection risk in small-scale communities like urban slums.

In the face of the COVID-19 pandemic, public health authorities around the world have experimented, in a short period of time, with various combinations of interventions at different scales. However, as the pandemic continues to progress, there is a growing need for tools and methodologies to quickly analyze the impact of these interventions and answer concrete questions regarding their effectiveness, range and temporality.

COMOKIT, the COVID-19 modeling kit, is such a tool. It is a computer model that allows intervention strategies to be explored in silico before their possible implementation phase. It can take into account important dimensions of policy actions, such as the heterogeneity of individual responses or the spatial aspect of containment strategies.

In COMOKIT, built using the agent-based modeling and simulation platform GAMA, the profiles, activities and interactions of people, person-to-person and environmental transmissions, individual clinical statuses, public health policies and interventions are explicitly represented and they all serve as a basis for describing the dynamics of the epidemic in a detailed and realistic representation of space.

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A global model of the 1918-19 Influenza Pandemic. It can be run to match history or explore counterfactual questions about the influence of World War I on the dynamics of the epidemic. Explores two theories of the location of the initial infection.