Computational Model Library

Agent based model of COVID19 spread with digital contact tracing

Stefano Picascia Jonatan Almagor | Published Tue Sep 28 14:21:31 2021 | Last modified Wed Oct 13 10:44:20 2021

Multi-layer network agent-based model of the progression of the COVID19 infection, digital contact tracing

Peer reviewed Minding Norms in an Epidemic Does Matter

Klaus Troitzsch | Published Sat Feb 27 10:04:04 2021 | Last modified Mon Sep 13 13:03:36 2021

This paper tries to shed some light on the mutual influence of citizen behaviour and the spread of a virus in an epidemic. While the spread of a virus from infectious to susceptible persons and the outbreak of an infection leading to more or less severe illness and, finally, to recovery and immunity or death has been modelled with different kinds of models in the past, the influence of certain behaviours to keep the epidemic low and to follow recommendations of others to apply these behaviours has rarely been modelled. The model introduced here uses a theory of the effect of norm invocations among persons to find out the effect of spreading norms interacts with the progress of an epidemic. Results show that norm invocations matter. The model replicates the histories of the COVID-19 epidemic in various region, including “second waves”, and shows that the calculation of the reproduction numbers from current reported infections usually overestimates the “real” but in practice unobservable reproduction number.

CINCH1 (Covid-19 INfection Control in Hospitals)

N Gotts | Published Sun Aug 29 13:13:03 2021

CINCH1 (Covid-19 INfection Control in Hospitals), is a prototype model of physical distancing for infection control among staff in University College London Hospital during the Covid-19 pandemic, developed at the University of Leeds, School of Geography. It models the movement of collections of agents in simple spaces under conflicting motivations of reaching their destination, maintaining physical distance from each other, and walking together with a companion. The model incorporates aspects of the Capability, Opportunity and Motivation of Behaviour (COM-B) Behaviour Change Framework developed at University College London Centre for Behaviour Change, and is aimed at informing decisions about behavioural interventions in hospital and other workplace settings during this and possible future outbreaks of highly contagious diseases. CINCH1 was developed as part of the SAFER (SARS-CoV-2 Acquisition in Frontline Health Care Workers – Evaluation to Inform Response) project
(https://www.ucl.ac.uk/behaviour-change/research/safer-sars-cov-2-acquisition-frontline-health-care-workers-evaluation-inform-response), funded by the UK Medical Research Council. It is written in Python 3.8, and built upon Mesa version 0.8.7 (copyright 2020 Project Mesa Team).

Holmestrand School Model

Jessica Dimka | Published Fri Jun 18 20:09:15 2021

The Holmestrand model is an epidemiological agent-based model. Its aim is to test hypotheses related to how the social and physical environment of a residential school for children with disabilities might influence the spread of an infectious disease epidemic among students and staff. Annual reports for the Holmestrand School for the Deaf (Norway) are the primary sources of inspiration for the modeled school, with additional insights drawn from other archival records for schools for children with disabilities in early 20th century Norway and data sources for the 1918 influenza pandemic. The model environment consists of a simplified boarding school that includes residential spaces for students and staff, classrooms, a dining room, common room, and an outdoor area. Students and staff engage in activities reflecting hourly schedules suggested by school reports. By default, a random staff member is selected as the first case and is infected with disease. Subsequent transmission is determined by agent movement and interactions between susceptible and infectious pairs.

EMMIT is an end-user developed agent-based simulation of malaria transmission. The simulation’s development is a case study demonstrating an approach for non-technical investigators to easily develop useful simulations of complex public health problems. We focused on malaria transmission, a major global public health problem, and insecticide resistance (IR), a major problem affecting malaria control. Insecticides are used to reduce transmission of malaria caused by the Plasmodium parasite that is spread by the Anopheles mosquito. However, the emergence and spread of IR in a mosquito population can diminish the insecticide’s effectiveness. IR results from mutations that produce behavioral changes or biochemical changes (such as detoxification enhancement, target site alterations) in the mosquito population that provide resistance to the insecticide. Evolutionary selection for the IR traits reduces the effectiveness of an insecticide favoring the resistant mosquito population. It has been suggested that biopesticides, and specifically those that are Late Life Acting (LLA), could address this problem. LLA insecticides exploit Plasmodium’s approximate 10-day extrinsic incubation period in the mosquito vector, a delay that limits malaria transmission to older infected mosquitoes. Since the proposed LLA insecticide delays mosquito death until after the exposed mosquito has a chance to produce several broods of offspring, reducing the selective pressure for resistance, it delays IR development and gives the insecticide longer effectivity. Such insecticides are designed to slow the evolution of IR thus maintaining their effectiveness for malaria control. For the IR problem, EMMIT shows that an LLA insecticide could work as intended, but its operational characteristics are critical, primarily the mean-time-to-death after exposure and the associated standard deviation. We also demonstrate the simulation’s extensibility to other malaria control measures, including larval source control and policies to mitigate the spread of IR. The simulation was developed using NetLogo as a case study of a simple but useful approach to public health research.

Peer reviewed MOOvPOPsurveillance

Aniruddha Belsare Matthew Gompper Joshua J Millspaugh | Published Tue Apr 4 17:03:40 2017 | Last modified Tue May 12 16:37:24 2020

MOOvPOPsurveillance was developed as a tool for wildlife agencies to guide collection and analysis of disease surveillance data that relies on non-probabilistic methods like harvest-based sampling.

Our model is hybrid agent-based and equation based model for human air-borne infectious diseases measles. It follows an SEIR (susceptible, exposed,infected, and recovered) type compartmental model with the agents moving be-tween the four state relating to infectiousness. However, the disease model canswitch back and forth between agent-based and equation based depending onthe number of infected agents. Our society model is specific using the datato create a realistic synthetic population for a county in Ireland. The modelincludes transportation with agents moving between their current location anddesired destination using predetermined destinations or destinations selectedusing a gravity model.

The purpose of the presented ABM is to explore how system resilience is affected by external disturbances and internal dynamics by using the stylized model of an agricultural land use system.

We explore land system resilience with a stylized land use model in which agents’ land use activities are affected by external shocks, agent interactions, and endogenous feedbacks. External shocks are designed as yield loss in crops, which is ubiquitous in almost every land use system where perturbations can occur due to e.g. extreme weather conditions or diseases. Agent interactions are designed as the transfer of buffer capacity from farmers who can and are willing to provide help to other farmers within their social network. For endogenous feedbacks, we consider land use as an economic activity which is regulated by markets — an increase in crop production results in lower price (a negative feedback) and an agglomeration of a land use results in lower production costs for the land use type (a positive feedback).

This model simulates the spread of anti-vaccine sentiments in cyber and physical space and how it creates emergence of clusters of anti-vacciners, which eventually lead to higher probablity of disease outbreaks.

Diffusion dynamics in small-world networks with heterogeneous consumers

Sebastiano Delre | Published Sat Sep 10 10:38:57 2011 | Last modified Sat Apr 27 20:18:30 2013

This model simulates diffusion curves and it allows to test how social influence, network structure and consumer heterogeneity affect their spreads and their speeds.

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