Computational Model Library

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Peer reviewed Virus Transmission with Super-spreaders

J M Applegate | Published Saturday, September 11, 2021

A curious aspect of the Covid-19 pandemic is the clustering of outbreaks. Evidence suggests that 80\% of people who contract the virus are infected by only 19% of infected individuals, and that the majority of infected individuals faile to infect another person. Thus, the dispersion of a contagion, $k$, may be of more use in understanding the spread of Covid-19 than the reproduction number, R0.

The Virus Transmission with Super-spreaders model, written in NetLogo, is an adaptation of the canonical Virus Transmission on a Network model and allows the exploration of various mitigation protocols such as testing and quarantines with both homogenous transmission and heterogenous transmission.

The model consists of a population of individuals arranged in a network, where both population and network degree are tunable. At the start of the simulation, a subset of the population is initially infected. As the model runs, infected individuals will infect neighboring susceptible individuals according to either homogenous or heterogenous transmission, where heterogenous transmission models super-spreaders. In this case, k is described as the percentage of super-spreaders in the population and the differing transmission rates for super-spreaders and non super-spreaders. Infected individuals either recover, at which point they become resistant to infection, or die. Testing regimes cause discovered infected individuals to quarantine for a period of time.

This software simulates cars and bicycles as traffic participants while crossing different crossroad designs such as roundabouts, protected crossroads and standard crossroads. It is written in Netlogo 6.2 and aims to identify safety characteristics of these layouts using agent-based modeling. Participants track the line of sight to each other and print them as an output alongside with the adjacent destination, used layout, count of collisions/cars/bicycles and time.

Detailed information can be found within the info tab of the program itself.

This is a Netlogo model which simulates car and bus/tram traffic in Augsburg, specifically between the districts Stadtbergen, Göggingen and the Königsplatz. People either use their cars or public transport to travel to one of their random destinations (Stadtbergen or Göggingen), performing some activity and then returning to their home. Attributes such as travel and waiting time as well as their happiness upon arriving are stored and have an impact on individuals on whether they would consider changing their mode of transport or not.

Holmestrand School Model

Jessica Dimka | Published Friday, June 18, 2021 | Last modified Friday, April 29, 2022

The Holmestrand model is an epidemiological agent-based model. Its aim is to test hypotheses related to how the social and physical environment of a residential school for children with disabilities might influence the spread of an infectious disease epidemic among students and staff. Annual reports for the Holmestrand School for the Deaf (Norway) are the primary sources of inspiration for the modeled school, with additional insights drawn from other archival records for schools for children with disabilities in early 20th century Norway and data sources for the 1918 influenza pandemic. The model environment consists of a simplified boarding school that includes residential spaces for students and staff, classrooms, a dining room, common room, and an outdoor area. Students and staff engage in activities reflecting hourly schedules suggested by school reports. By default, a random staff member is selected as the first case and is infected with disease. Subsequent transmission is determined by agent movement and interactions between susceptible and infectious pairs.

MELBIS-V1 is a spatially explicit agent-based model that allows the geospatial simulation of the decision-making process of newcomers arriving in the bilingual cities and boroughs of the island of Montreal, Quebec in CANADA, and the resulting urban segregation spatial patterns. The model was implemented in NetLogo, using geospatial raster datasets of 120m spatial resolution.

MELBIS-V2 enhances MELBIS-V1 to implement and simulate the decision-making processes of incoming immigrants, and to analyze the resulting spatial patterns of segregation as immigrants arrive and settle in various cities in Canada. The arrival and segregation of immigrants is modeled with MELBIS-V2 and compared for three major Canadian immigration gateways, including the City of Toronto, Metro Vancouver, and the City of Calgary.

Zombies

Jennifer Badham | Published Tuesday, June 08, 2021

Zombies move toward humans and humans move (faster) away from zombies. They fight if they meet, and humans who lose become zombies.

EMMIT is an end-user developed agent-based simulation of malaria transmission. The simulation’s development is a case study demonstrating an approach for non-technical investigators to easily develop useful simulations of complex public health problems. We focused on malaria transmission, a major global public health problem, and insecticide resistance (IR), a major problem affecting malaria control. Insecticides are used to reduce transmission of malaria caused by the Plasmodium parasite that is spread by the Anopheles mosquito. However, the emergence and spread of IR in a mosquito population can diminish the insecticide’s effectiveness. IR results from mutations that produce behavioral changes or biochemical changes (such as detoxification enhancement, target site alterations) in the mosquito population that provide resistance to the insecticide. Evolutionary selection for the IR traits reduces the effectiveness of an insecticide favoring the resistant mosquito population. It has been suggested that biopesticides, and specifically those that are Late Life Acting (LLA), could address this problem. LLA insecticides exploit Plasmodium’s approximate 10-day extrinsic incubation period in the mosquito vector, a delay that limits malaria transmission to older infected mosquitoes. Since the proposed LLA insecticide delays mosquito death until after the exposed mosquito has a chance to produce several broods of offspring, reducing the selective pressure for resistance, it delays IR development and gives the insecticide longer effectivity. Such insecticides are designed to slow the evolution of IR thus maintaining their effectiveness for malaria control. For the IR problem, EMMIT shows that an LLA insecticide could work as intended, but its operational characteristics are critical, primarily the mean-time-to-death after exposure and the associated standard deviation. We also demonstrate the simulation’s extensibility to other malaria control measures, including larval source control and policies to mitigate the spread of IR. The simulation was developed using NetLogo as a case study of a simple but useful approach to public health research.

NetPlop is a presentation editor built entirely in NetLogo, an agent-based modelling environment. The NetPlop Editor includes a variety of tools to design slide decks, and the Viewer allows these decks to be dis-played to an enraptured audience. A key feature of NetPlop is the ability to embed agent-based models. NetPlop was developed for SIGBOVIK 2021.

The Netlogo model is a conceptualization of the Moria refugee camp, capturing the household demographics of refugees in the camp, a theoretical friendship network based on values, and an abstraction of their daily activities. The model then simulates how Covid-19 could spread through the camp if one refugee is exposed to the virus, utilizing transmission probabilities and the stages of disease progression of Covid-19 from susceptible to exposed to asymptomatic / symptomatic to mild / severe to recovered from literature. The model also incorporates various interventions - PPE, lockdown, isolation of symptomatic refugees - to analyze how they could mitigate the spread of the virus through the camp.

Netlogo model that shows how the cooling process determines the quality of a solution in simulated annealing using Metropolis algorithm.

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