Computational Model Library

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This is an extension of the basic Suceptible, Infected, Recovered (SIR) model. This model explores the spread of disease in two spaces, one a treatment, and one a control. Through the modeling options, one can explore how changing assumptions about the number of susceptible people, starting number of infected people, the disease’s infection probability, and average duration impacts the outcome. In addition, this version allows users to explore how public health interventions like social distancing, masking, and isolation can affect the number of people infected. The model shows that the interactions of agents, and the interventions can drastically affect the results of the model.

We used the model in our course about COVID-19: https://www.csats.psu.edu/science-of-covid19

This model is an agent-based simulation written in Python 2.7, which simulates the cost of social care in an ageing UK population. The simulation incorporates processes of population change which affect the demand for and supply of social care, including health status, partnership formation, fertility and mortality. Fertility and mortality rates are drawn from UK population data, then projected forward to 2050 using the methods developed by Lee and Carter 1992.

The model demonstrates that rising life expectancy combined with lower birthrates leads to growing social care costs across the population. More surprisingly, the model shows that the oft-proposed intervention of raising the retirement age has limited utility; some reductions in costs are attained initially, but these reductions taper off beyond age 70. Subsequent work has enhanced and extended this model by adding more detail to agent behaviours and familial relationships.

The version of the model provided here produces outputs in a format compatible with the GEM-SA uncertainty quantification software by Kennedy and O’Hagan. This allows sensitivity analyses to be performed using Gaussian Process Emulation.

CINCH1 (Covid-19 INfection Control in Hospitals), is a prototype model of physical distancing for infection control among staff in University College London Hospital during the Covid-19 pandemic, developed at the University of Leeds, School of Geography. It models the movement of collections of agents in simple spaces under conflicting motivations of reaching their destination, maintaining physical distance from each other, and walking together with a companion. The model incorporates aspects of the Capability, Opportunity and Motivation of Behaviour (COM-B) Behaviour Change Framework developed at University College London Centre for Behaviour Change, and is aimed at informing decisions about behavioural interventions in hospital and other workplace settings during this and possible future outbreaks of highly contagious diseases. CINCH1 was developed as part of the SAFER (SARS-CoV-2 Acquisition in Frontline Health Care Workers – Evaluation to Inform Response) project
(https://www.ucl.ac.uk/behaviour-change/research/safer-sars-cov-2-acquisition-frontline-health-care-workers-evaluation-inform-response), funded by the UK Medical Research Council. It is written in Python 3.8, and built upon Mesa version 0.8.7 (copyright 2020 Project Mesa Team).

EMMIT is an end-user developed agent-based simulation of malaria transmission. The simulation’s development is a case study demonstrating an approach for non-technical investigators to easily develop useful simulations of complex public health problems. We focused on malaria transmission, a major global public health problem, and insecticide resistance (IR), a major problem affecting malaria control. Insecticides are used to reduce transmission of malaria caused by the Plasmodium parasite that is spread by the Anopheles mosquito. However, the emergence and spread of IR in a mosquito population can diminish the insecticide’s effectiveness. IR results from mutations that produce behavioral changes or biochemical changes (such as detoxification enhancement, target site alterations) in the mosquito population that provide resistance to the insecticide. Evolutionary selection for the IR traits reduces the effectiveness of an insecticide favoring the resistant mosquito population. It has been suggested that biopesticides, and specifically those that are Late Life Acting (LLA), could address this problem. LLA insecticides exploit Plasmodium’s approximate 10-day extrinsic incubation period in the mosquito vector, a delay that limits malaria transmission to older infected mosquitoes. Since the proposed LLA insecticide delays mosquito death until after the exposed mosquito has a chance to produce several broods of offspring, reducing the selective pressure for resistance, it delays IR development and gives the insecticide longer effectivity. Such insecticides are designed to slow the evolution of IR thus maintaining their effectiveness for malaria control. For the IR problem, EMMIT shows that an LLA insecticide could work as intended, but its operational characteristics are critical, primarily the mean-time-to-death after exposure and the associated standard deviation. We also demonstrate the simulation’s extensibility to other malaria control measures, including larval source control and policies to mitigate the spread of IR. The simulation was developed using NetLogo as a case study of a simple but useful approach to public health research.

The Netlogo model is a conceptualization of the Moria refugee camp, capturing the household demographics of refugees in the camp, a theoretical friendship network based on values, and an abstraction of their daily activities. The model then simulates how Covid-19 could spread through the camp if one refugee is exposed to the virus, utilizing transmission probabilities and the stages of disease progression of Covid-19 from susceptible to exposed to asymptomatic / symptomatic to mild / severe to recovered from literature. The model also incorporates various interventions - PPE, lockdown, isolation of symptomatic refugees - to analyze how they could mitigate the spread of the virus through the camp.

Port of Mars simplified

Marco Janssen | Published Tuesday, January 14, 2020

This is a simulation model to explore possible outcomes of the Port of Mars cardgame. Port of Mars is a resource allocation game examining how people navigate conflicts between individual goals and common interests relative to shared resources. The game involves five players, each of whom must decide how much of their time and effort to invest in maintaining public infrastructure and renewing shared resources and how much to expend in pursuit of their individual goals. In the game, “Upkeep” is a number that represents the physical health of the community. This number begins at 100 and goes down by twenty-five points each round, representing resource consumption and wear and tear on infrastructure. If that number reaches zero, the community collapses and everyone dies.

In the face of the COVID-19 pandemic, public health authorities around the world have experimented, in a short period of time, with various combinations of interventions at different scales. However, as the pandemic continues to progress, there is a growing need for tools and methodologies to quickly analyze the impact of these interventions and answer concrete questions regarding their effectiveness, range and temporality.

COMOKIT, the COVID-19 modeling kit, is such a tool. It is a computer model that allows intervention strategies to be explored in silico before their possible implementation phase. It can take into account important dimensions of policy actions, such as the heterogeneity of individual responses or the spatial aspect of containment strategies.

In COMOKIT, built using the agent-based modeling and simulation platform GAMA, the profiles, activities and interactions of people, person-to-person and environmental transmissions, individual clinical statuses, public health policies and interventions are explicitly represented and they all serve as a basis for describing the dynamics of the epidemic in a detailed and realistic representation of space.

Peer reviewed NetLogo model of USA mass shootings

Smarzhevskiy Ivan | Published Tuesday, September 24, 2019 | Last modified Tuesday, April 14, 2020

Is the mass shooter a maniac or a relatively normal person in a state of great stress? According to the FBI report (Silver, J., Simons, A., & Craun, S. (2018). A Study of the Pre-Attack Behaviors of Active Shooters in the United States Between 2000 – 2013. Federal Bureau of Investigation, U.S. Department of Justice,Washington, D.C. 20535.), only 25% of the active shooters were known to have been diagnosed by a mental health professional with a mental illness of any kind prior to the offense.
The main objects of the model are the humans and the guns. The main factors influencing behavior are the population size, the number of people with mental disabilities (“psycho” in the model terminology) per 100,000 population, the total number of weapons (“guns”) in the population, the availability of guns for humans, the intensity of stressors affecting humans and the threshold level of stress, upon reaching which a person commits an act of mass shooting.
The key difference (in the model) between a normal person and a psycho is that a psycho accumulates stressors and, upon reaching a threshold level, commits an act of mass shooting. A normal person is exposed to stressors, but reaching the threshold level for killing occurs only when the simultaneous effect of stressors on him exceeds this level.
The population dynamics are determined by the following factors: average (normally distributed) life expectancy (“life_span” attribute of humans) and population growth with the percentage of newborns set by the value of the TickReprRatio% slider of the current population volume from 16 to 45 years old.Thus, one step of model time corresponds to a year.

The application of a smartphone application to register physical encounters between individuals is considered by public health authorities, as a means to reduce the number of infections in the 2020 COVID-19 pandemic. The general idea is that continuous registration of all other smartphones in the vicinity of an individual’s smartphone potentially enables early warning of the owners of the other smartphones, in case the individual is tested positive as infected. Those other individuals can then go into isolation and be considered for testing. The purpose of the present simulation is to explore the potential effects of this application on frequencies of infection, isolation, and positive and negative infection test results.

This model was built to estimate the impacts of exogenous fodder input and credit loans services on livelihood, rangeland health and profits of pastoral production in a small holder pastoral household in the arid steppe rangeland of Inner Mongolia, China. The model simulated the long-term dynamic of herd size and structure, the forage demand and supply, the cash flow, and the situation of loan debt under three different stocking strategies: (1) No external fodder input, (2) fodders were only imported when natural disaster occurred, and (3) frequent import of external fodder, with different amount of available credit loans. Monte-Carlo method was used to address the influence of climate variability.

Displaying 10 of 35 results health clear

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