Computational Model Library

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An unintended consequence of low cost maritime travel may be hyperconnectedness, creating social situations where information can be readily passed before it is verified- an issue not limited to modern digitally connected societies. In traditional Coast Salish societies, the peoples of what is now Western Washington and Southwestern British Columbia, oral traditions were vertified through a process called witnessing. Witnesses would be trained to recount and verify oral history and traditional teachings at high fidelity. Here, a simple model based on dual inheritance approaches to genes and culture, is used to compare this specific form of verifying socially important information compared to modern mass communication. The model suggests that witnessing is a high fidelity form of transmitting knowledge with a low error rate, more in line with modern apprenticeships than mass communication. Social mechanisms such as witnessing provide solutions to issues faced in contemporary discourse where the validity of information and even fact checking mechanisms may be biased or counterfactual. This effort also demonstrates the utillity of using modeling approaches to highlight how specific, historically contingent institutions such as witnesses can be drawn upon to model potential solutions to contemporary issues solved in the past in traditional Coast Salish practice.

GenoScope

Kristin Crouse | Published Wednesday, May 29, 2024 | Last modified Wednesday, April 09, 2025

GenoScope is a modular agent-based model designed to simulate how cells respond to environmental stressors or other treatment conditions across species. Genes, treatment conditions, and cell physiology outcomes are represented as interacting agents that influence each other’s behavior over time. Rather than imposing fixed interaction rules, GenoScope initializes with randomized regulatory logic and calibrates rule sets based on empirical data. Calibration is grounded in a common-garden experiment involving 16 mammalian species—including humans, dolphins, bats, and camels—exposed to varying levels of temperature, glucose, and oxygen. This comparative approach enables the identification of mechanisms by which animal cells achieve robustness under extreme environmental conditions.

HyperMu’NmGA - Effect of Hypermutation Cycles in a NetLogo Minimal Genetic Algorithm

Cosimo Leuci | Published Tuesday, October 27, 2020 | Last modified Sunday, July 31, 2022

A minimal genetic algorithm was previously developed in order to solve an elementary arithmetic problem. It has been modified to explore the effect of a mutator gene and the consequent entrance into a hypermutation state. The phenomenon seems relevant in some types of tumorigenesis and in a more general way, in cells and tissues submitted to chronic sublethal environmental or genomic stress.
For a long time, some scholars suppose that organisms speed up their own evolution by varying mutation rate, but evolutionary biologists are not convinced that evolution can select a mechanism promoting more (often harmful) mutations looking forward to an environmental challenge.
The model aims to shed light on these controversial points of view and it provides also the features required to check the role of sex and genetic recombination in the mutator genes diffusion.

00b SimEvo_V5.08 NetLogo

Garvin Boyle | Published Saturday, October 05, 2019

In 1985 Dr Michael Palmiter, a high school teacher, first built a very innovative agent-based model called “Simulated Evolution” which he used for teaching the dynamics of evolution. In his model, students can see the visual effects of evolution as it proceeds right in front of their eyes. Using his schema, small linear changes in the agent’s genotype have an exponential effect on the agent’s phenotype. Natural selection therefore happens quickly and effectively. I have used his approach to managing the evolution of competing agents in a variety of models that I have used to study the fundamental dynamics of sustainable economic systems. For example, here is a brief list of some of my models that use “Palmiter Genes”:
- ModEco - Palmiter genes are used to encode negotiation strategies for setting prices;
- PSoup - Palmiter genes are used to control both motion and metabolic evolution;
- TpLab - Palmiter genes are used to study the evolution of belief systems;
- EffLab - Palmiter genes are used to study Jevon’s Paradox, EROI and other things.

00 PSoup V1.22 – Primordial Soup

Garvin Boyle | Published Thursday, April 13, 2017

PSoup is an educational program in which evolution is demonstrated, on the desk-top, as you watch. Blind bugs evolve sophisticated heuristic search algorithms to be the best at finding food fast.

Peer reviewed Evolution of Sex

Kristin Crouse | Published Sunday, June 05, 2016 | Last modified Monday, February 15, 2021

Evolution of Sex is a NetLogo model that illustrates the advantages and disadvantages of sexual and asexual reproductive strategies. It seeks to demonstrate the answer to the question “Why do we have sex?”

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