This agent-based model explores the dynamics between human behavior and vaccination strategies during COVID-19 pandemics. It examines how individual risk perceptions influence behaviors and subsequently affect epidemic outcomes in a simulated metropolitan area resembling New York City from December 2020 to May 2021.

Agents modify their daily activities—deciding whether to travel to densely populated urban centers or stay in less crowded neighborhoods—based on their risk perception. This perception is influenced by factors such as risk perception threshold, risk tolerance personality, mortality rate, disease prevalence, and the average number of contacts per agent in crowded settings. Agent characteristics are carefully calibrated to reflect New York City demographics, including age distribution and variations in infection probability and mortality rates across these groups. The agents can experience six distinct health statuses: susceptible, exposed, infectious, recovered from infection, dead, and vaccinated (SEIRDV). The simulation focuses on the Iota and Alpha variants, the dominant strains in New York City during the period.

We simulate six scenarios divided into three main categories:
1. A baseline model without vaccinations where agents exhibit no risk perception and are indifferent to virus transmission and disease prevalence.
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This is a basic Susceptible, Infected, Recovered (SIR) model. This model explores the spread of disease in a space. In particular, it explores how changing assumptions about the number of susceptible people, starting number of infected people, as well as the disease’s infection probability, and average duration of infection. The model shows that the interactions of agents can drastically affect the results of the model.

We used it in our course on COVID-19: https://www.csats.psu.edu/science-of-covid19

The Holmestrand model is an epidemiological agent-based model. Its aim is to test hypotheses related to how the social and physical environment of a residential school for children with disabilities might influence the spread of an infectious disease epidemic among students and staff. Annual reports for the Holmestrand School for the Deaf (Norway) are the primary sources of inspiration for the modeled school, with additional insights drawn from other archival records for schools for children with disabilities in early 20th century Norway and data sources for the 1918 influenza pandemic. The model environment consists of a simplified boarding school that includes residential spaces for students and staff, classrooms, a dining room, common room, and an outdoor area. Students and staff engage in activities reflecting hourly schedules suggested by school reports. By default, a random staff member is selected as the first case and is infected with disease. Subsequent transmission is determined by agent movement and interactions between susceptible and infectious pairs.

CINCH1 (Covid-19 INfection Control in Hospitals), is a prototype model of physical distancing for infection control among staff in University College London Hospital during the Covid-19 pandemic, developed at the University of Leeds, School of Geography. It models the movement of collections of agents in simple spaces under conflicting motivations of reaching their destination, maintaining physical distance from each other, and walking together with a companion. The model incorporates aspects of the Capability, Opportunity and Motivation of Behaviour (COM-B) Behaviour Change Framework developed at University College London Centre for Behaviour Change, and is aimed at informing decisions about behavioural interventions in hospital and other workplace settings during this and possible future outbreaks of highly contagious diseases. CINCH1 was developed as part of the SAFER (SARS-CoV-2 Acquisition in Frontline Health Care Workers – Evaluation to Inform Response) project
(https://www.ucl.ac.uk/behaviour-change/research/safer-sars-cov-2-acquisition-frontline-health-care-workers-evaluation-inform-response), funded by the UK Medical Research Council. It is written in Python 3.8, and built upon Mesa version 0.8.7 (copyright 2020 Project Mesa Team).

Pandemic (pip install pandemic)

An agent model in which commuting, compliance, testing and contagion parameters drive infection in a population of thousands of millions. Agents follow Ornstein-Uhlenbeck processes in the plane and collisions drive transmission. Results are stored at SwarmPrediction.com for further analysis, and can be retrieved by anyone.

This is a very simple simulation that in a special case can be shown to be approximated by a compartmental model with time varying infection rate.

This is an extension of the basic Suceptible, Infected, Recovered (SIR) model. This model explores the spread of disease in two spaces, one a treatment, and one a control. Through the modeling options, one can explore how changing assumptions about the number of susceptible people, starting number of infected people, the disease’s infection probability, and average duration impacts the outcome. In addition, this version allows users to explore how public health interventions like social distancing, masking, and isolation can affect the number of people infected. The model shows that the interactions of agents, and the interventions can drastically affect the results of the model.

We used the model in our course about COVID-19: https://www.csats.psu.edu/science-of-covid19

Model of the Corona pandemic outbreak

The COVID-19 ABM aims to predict the qualitative behaviour of the CoViD-19 epidemic dynamics for the greater region of Salzburg City. Specifically, by means of scenario testing, it aims to help assessing how containment interventions can allow a stepwise relaxation of the lockdown without risking a new outbreak.

The application of a smartphone application to register physical encounters between individuals is considered by public health authorities, as a means to reduce the number of infections in the 2020 COVID-19 pandemic. The general idea is that continuous registration of all other smartphones in the vicinity of an individual’s smartphone potentially enables early warning of the owners of the other smartphones, in case the individual is tested positive as infected. Those other individuals can then go into isolation and be considered for testing. The purpose of the present simulation is to explore the potential effects of this application on frequencies of infection, isolation, and positive and negative infection test results.

This is a model of root disease spread between trees in the landscape. The disease spreads via two transmission processes: (a) root contact/root graft transmission between adjacent trees and (b) insect vectors that carry spores between trees. Full details can be found in the “Info” tab in the model and in the readme file in the GitHub repository.

This paper tries to shed some light on the mutual influence of citizen behaviour and the spread of a virus in an epidemic. While the spread of a virus from infectious to susceptible persons and the outbreak of an infection leading to more or less severe illness and, finally, to recovery and immunity or death has been modelled with different kinds of models in the past, the influence of certain behaviours to keep the epidemic low and to follow recommendations of others to apply these behaviours has rarely been modelled. The model introduced here uses a theory of the effect of norm invocations among persons to find out the effect of spreading norms interacts with the progress of an epidemic. Results show that norm invocations matter. The model replicates the histories of the COVID-19 epidemic in various region, including “second waves” (but only until the end of 2021 as afterwards the official statistics ceased to be reliable as many infected persons did not report their positive test results after countermeasures were relieved), and shows that the calculation of the reproduction numbers from current reported infections usually overestimates the “real” but in practice unobservable reproduction number.