Computational Model Library

HyperMu’NmGA - Effect of Hypermutation Cycles in a NetLogo Minimal Genetic Algorithm (version 1.0.0)

A minimal genetic algorithm was preliminarily developed to search for the solution of an elementary arithmetic problem. It has been modified to explore the effect of a mutator gene and the consequent entrance into a hypermutation state. The phenomenon is particularly important in some types of tumorigenesis and in a more general way, in cells and tissues submitted to chronic sublethal environmental or genomic stress.
Since a long time, some scholars suppose that organisms speed up their own evolution by varying mutation rate, but evolutionary biologists are not convinced that evolution can select a mechanism promoting more (often harmful) mutations looking forward an environmental challenge. The aim of the model is to shed light on these controversial points of views.

HyperMu-MGA.gif

Release Notes

See ODD-protocol or info-tab attached to the code file

Download Version 1.0.0
Version Submitter First published Last modified Status
1.0.0 Cosimo Leuci Tue Oct 27 21:15:40 2020 Tue Oct 27 21:15:40 2020 Published Peer Reviewed https://doi.org/10.25937/gdwp-ej02

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