I am a PhD Candidate in the Biological Anthropology program at the University of Minnesota. My research involves using agent-based models combined with field research to test a broad range of hypotheses in biology. I have created a model, B3GET, which simulates the evolution of virtual organisms to better understand the relationships between growth and development, life history and reproductive strategies, mating strategies, foraging strategies, and how ecological factors drive these relationships. I also conduct field research to better model the behavior of these virtual organisms. Here I am pictured with an adult male gelada in Ethiopia!
I specialize in writing agent-based models for both research in and the teaching of subjects including: biology, genetics, evolution, demography, and behavior.
For my dissertation research, I have developed “B3GET,” an agent-based model which simulates populations of virtual organisms evolving over generations, whose evolutionary outcomes reflect the selection pressures of their environment. The model simulates several factors considered important in biology, including life history trade-offs, investment in body size, variation in aggression, sperm competition, infanticide, and competition over access to food and mates. B3GET calculates each agent’s ‘decision-vectors’ from its diploid chromosomes and current environmental context. These decision-vectors dictate movement, body growth, desire to mate and eat, and other agent actions. Chromosomes are modified during recombination and mutation, resulting in behavioral strategies that evolve over generations. Rather than impose model parameters based on a priori assumptions, I have used an experimental evolution procedure to evolve traits that enabled populations to persist. Seeding a succession of populations with the longest surviving genotype from each run resulted in the evolution of populations that persisted indefinitely. I designed B3GET for my dissertation, but it has an indefinite number of applications for other projects in biology. B3GET helps answer fundamental questions in evolutionary biology by offering users a virtual field site to precisely track the evolution of organismal populations. Researchers can use B3GET to: (1) investigate how populations vary in response to ecological pressures; (2) trace evolutionary histories over indefinite time scales and generations; (3) track an individual for every moment of their life from conception to post-mortem decay; and (4) create virtual analogues of living species, including primates like baboons and chimpanzees, to answer species-specific questions. Users are able to save, edit, and import population and genotype files, offering an array of possibilities for creating controlled biological experiments.
Primate evolutionary biologist and geneticist at the University of Texas at Austin
I conduct long-term behavioral and ecological field research on several species in the primate community of Amazonian Ecuador to investigate the ways in which ecological conditions (such as the abundance and distribution of food resources) and the strategies of conspecifics together shape primate behavior and social relationships and ultimately determine the kinds of societies we see primates living in. This is a crucial and central focus in evolutionary anthropology, as understanding the ways in which behavior and social systems are shaped by environmental pressures is a fundamental part of the discipline.
I complement my field studies with molecular genetic laboratory work and agent-based simulation modeling in order to address issues that are typically difficult to explore through observational studies alone, including questions about dispersal behavior, gene flow, mating patterns, population structure, and the fitness consequences of individual behavior. In collaboration with colleagues, I have also started using molecular techniques to investigate a number of broader questions concerning the evolutionary history, social systems, and ecological roles of various New World primates.
Ken Buetow is a human genetics and genomics researcher who leverages computational tools to understand complex traits such as cancer, liver disease, and obesity. He currently serves as director of Computational Sciences and Informatics program for Complex Adaptive Systems at Arizona State University ([email protected]), is a professor in the School of Life Sciences in ASU’s College of Liberal Arts and Sciences; is a core faculty in the Center for Evolution and Medicine in the Biodesign Institute at ASU; and is director of bioinformatics and data management for the National Biomarker Development Alliance.
Professor Buetow previously served as the Founding Director of the Center for Biomedical Informatics and Information Technology within the National Institutes of Health’s National Cancer Institute.
I’m interested in inter-individual interactions in general, demo-genetics and group behaviour. I’m currently working on locusts. Visit my website for more info.
I am interested in the interface between biology and computation. I am especially focused on modelling and simulation of evolutionary processes.
Ecology and population dynamics of fish and wildlife populations, epidemiology, biometry
complex systems science; implementation science; agent based modeling; health care infrastructure and population health; public health
PhD student at University of Toronto: memes, social networks, contagion, agent based modeling, synthetic populations
neural computation, population dynamics
STDs, HIV, Hepatitis C in prison populations